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黄体的调控:毒理学研究的一个模型系统

Control of the corpus luteum: a model system for toxicology research.

作者信息

Freeman M E

出版信息

Environ Health Perspect. 1981 Apr;38:51-4. doi: 10.1289/ehp.813851.

DOI:10.1289/ehp.813851
PMID:7238446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1568423/
Abstract

The rodent corpus luteum is an ephemeral structure releasing progesterone for only a few hours rather than several days. However, in response to the mating stimulus, sufficient prolactin is released from the pituitary gland in a unique pattern to activate the corpus luteum and maintain it in a secretory state for several days. Progesterone, secreted from the corpus luteum, prolongs the secretion of prolactin, while the uterus may secrete a substance which terminates the functional life of the corpus luteum directly and also acts upon he prolactin secretory apparatus within the hypothalamopituitary axis to terminate prolactin secretion.

摘要

啮齿动物的黄体是一种短暂的结构,仅释放数小时而非数天的孕酮。然而,在交配刺激的作用下,垂体以一种独特的模式释放足够的催乳素,以激活黄体并使其维持分泌状态数天。黄体分泌的孕酮会延长催乳素的分泌,而子宫可能会分泌一种物质,该物质直接终止黄体的功能寿命,同时也作用于下丘脑 - 垂体轴内的催乳素分泌装置以终止催乳素的分泌。

相似文献

1
Control of the corpus luteum: a model system for toxicology research.黄体的调控:毒理学研究的一个模型系统
Environ Health Perspect. 1981 Apr;38:51-4. doi: 10.1289/ehp.813851.
2
The control of progesterone secretion during the estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy.大鼠发情周期和早期假孕期间孕酮分泌的调控:与假孕黄体挽救相关的催乳素、促性腺激素和类固醇水平
Endocrinology. 1975 Jan;96(1):219-26. doi: 10.1210/endo-96-1-219.
3
Role of prolactin in regulating gonadotropin secretion and gonad function in female rats.催乳素在调节雌性大鼠促性腺激素分泌及性腺功能中的作用。
Fed Proc. 1980 Jun;39(8):2571-6.
4
Prolactin: the initial luteotropic stimulus of pseudopregnancy in the rat.催乳素:大鼠假孕的初始促黄体刺激因素。
Endocrinology. 1976 Jun;98(6):1370-7. doi: 10.1210/endo-98-6-1370.
5
Effect of prolactin on luteal functions in the cyclic rat: positive correlation between luteinizing hormone-stimulated adenylyl cyclase activity and progesterone secretion; role in corpus luteum rescue of the morning surge of prolactin on day 3 of pseudopregnancy.
Endocrinology. 1980 Apr;106(4):1265-9.
6
Temporal aspects of the involvement of the uterus and prolactin in the establishment of luteinizing hormones-dependent progesterone secretion in the rat.大鼠中子宫和催乳素参与促黄体生成素依赖性孕酮分泌建立过程的时间方面。
Endocrinology. 1980 Oct;107(4):1112-6. doi: 10.1210/endo-107-4-1112.
7
Interactions among estrogen, prolactin and luteinizing hormone at the level of adenylyl cyclase in the corpus luteum: findings and physiological correlates.
Adv Exp Med Biol. 1979;112:663-77. doi: 10.1007/978-1-4684-3474-3_73.
8
Progesterone and the control of functional luteolysis, of secretion of prolactin and of pituitary LHRH responsiveness. A study with pseudopregnant rats kept in alternating and constant lighting conditions.孕酮与功能性黄体溶解的控制、催乳素分泌以及垂体促性腺激素释放激素反应性的研究。对处于交替光照和恒定光照条件下的假孕大鼠的一项研究。
Neuroendocrinology. 1985 Jul;41(1):52-9. doi: 10.1159/000124153.
9
[Maintenance of the corpus luteum by estrogen in the rat].
Nihon Sanka Fujinka Gakkai Zasshi. 1971 Jun;23(6):491-500.
10
Corpus luteum function and adenylyl cyclase stimulability in the rat after an estradiol benzoate-induced ovulatory surge of luteinizing hormone: role of prolactin.
Endocrinology. 1980 Jan;106(1):382-9. doi: 10.1210/endo-106-1-382.

本文引用的文献

1
Regulation of nocturnal prolactin surges during pregnancy in the rat.
Endocrinology. 1980 Jun;106(6):1670-6. doi: 10.1210/endo-106-6-1670.
2
The pattern of prolactin secretion during pseudopregnancy in the rat: a daily nocturnal surge.
Endocrinology. 1972 May;90(5):1292-4. doi: 10.1210/endo-90-5-1292.
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Endocrinology. 1972 Apr;90(4):1125-7. doi: 10.1210/endo-90-4-1125.
4
Progesterone and pregn-4-en-20 alpha-ol-3-one in ovarian venous blood during various reproductive states in the rat.大鼠不同生殖状态下卵巢静脉血中的孕酮和孕-4-烯-20α-醇-3-酮
Endocrinology. 1968 Feb;82(2):333-41. doi: 10.1210/endo-82-2-333.
5
A comparative study of serum progesterone levels in pregnancy and in various types of pseudopregnancy in the rat.大鼠孕期与各种类型假孕血清孕酮水平的比较研究。
Endocrinology. 1974 Jul;95(1):275-9. doi: 10.1210/endo-95-1-275.
6
Temporal aspects of the regulation of corpus luteum function by luteinizing hormone, prolactin and placental luteotrophin during the first half of pregnancy in the rat.
Endocrinology. 1974 Jul;95(1):260-74. doi: 10.1210/endo-95-1-260.
7
Ovarian and hypothalamic control of the daily surges of prolactin secretion during pseudopregnancy in the rat.
Endocrinology. 1974 Mar;94(3):875-82. doi: 10.1210/endo-94-3-875.
8
Progravid phase of the rat reproductive cycle: day to day changes in peripheral plasma progestin concentrations.
Endocrinology. 1973 Mar;92(3):949-52. doi: 10.1210/endo-92-3-949.
9
Effect of hysterectomy on serum luteinizing hormone concentrations and on corpus luteum function in the rat.子宫切除术对大鼠血清促黄体生成素浓度及黄体功能的影响。
Endocrinology. 1976 May;98(5):1228-34. doi: 10.1210/endo-98-5-1228.
10
The control of progesterone secretion during the estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy.大鼠发情周期和早期假孕期间孕酮分泌的调控:与假孕黄体挽救相关的催乳素、促性腺激素和类固醇水平
Endocrinology. 1975 Jan;96(1):219-26. doi: 10.1210/endo-96-1-219.