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黄体的调控:毒理学研究的一个模型系统

Control of the corpus luteum: a model system for toxicology research.

作者信息

Freeman M E

出版信息

Environ Health Perspect. 1981 Apr;38:51-4. doi: 10.1289/ehp.813851.

Abstract

The rodent corpus luteum is an ephemeral structure releasing progesterone for only a few hours rather than several days. However, in response to the mating stimulus, sufficient prolactin is released from the pituitary gland in a unique pattern to activate the corpus luteum and maintain it in a secretory state for several days. Progesterone, secreted from the corpus luteum, prolongs the secretion of prolactin, while the uterus may secrete a substance which terminates the functional life of the corpus luteum directly and also acts upon he prolactin secretory apparatus within the hypothalamopituitary axis to terminate prolactin secretion.

摘要

啮齿动物的黄体是一种短暂的结构,仅释放数小时而非数天的孕酮。然而,在交配刺激的作用下,垂体以一种独特的模式释放足够的催乳素,以激活黄体并使其维持分泌状态数天。黄体分泌的孕酮会延长催乳素的分泌,而子宫可能会分泌一种物质,该物质直接终止黄体的功能寿命,同时也作用于下丘脑 - 垂体轴内的催乳素分泌装置以终止催乳素的分泌。

相似文献

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[Maintenance of the corpus luteum by estrogen in the rat].
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本文引用的文献

1
Regulation of nocturnal prolactin surges during pregnancy in the rat.
Endocrinology. 1980 Jun;106(6):1670-6. doi: 10.1210/endo-106-6-1670.
2
The pattern of prolactin secretion during pseudopregnancy in the rat: a daily nocturnal surge.
Endocrinology. 1972 May;90(5):1292-4. doi: 10.1210/endo-90-5-1292.
3
Semicircadian rhythm in plasma levels of prolactin during early gestation in the rat.
Endocrinology. 1972 Apr;90(4):1125-7. doi: 10.1210/endo-90-4-1125.

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