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体外肿瘤细胞社会行为与体内恶性肿瘤之间关系的一项研究贡献。

A contribution to the relationship between tumour cell social behaviour in vitro and malignancy in vivo.

作者信息

Veselý P, Kren V, Urbanec P, Krchnáková E

出版信息

Folia Biol (Praha). 1981;27(2):140-7.

PMID:7238947
Abstract

Membrane activity of high malignant (grade IV in the immunogenetic test of malignancy) cells was found to continue along the contacting edge after random collision with normal cells in vitro, as demonstrated by the high resolution time-lapse cinemicrography. This preservation of surface activity was the main difference in social behaviour of high and low malignant rat tumour cells upon random collision with normal cells in four lines of tumour cells investigated.

摘要

通过高分辨率延时电影显微镜观察发现,在体外与正常细胞随机碰撞后,高恶性(恶性免疫遗传学检测中为IV级)细胞的膜活性会沿着接触边缘持续存在。在所研究的四组肿瘤细胞系中,高恶性和低恶性大鼠肿瘤细胞在与正常细胞随机碰撞时,表面活性的这种保留是它们社交行为的主要差异。

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