Combined carcinogenic action of chrysotile asbestos dust and N-nitrosodiethylamine on the respiratory tract of Syrian golden hamsters.
作者信息
Küng-Vösamäe A, Vinkmann F
出版信息
IARC Sci Publ. 1980(30):305-10.
PMID:7239649
Abstract
The combined carcinogenic activity of intratracheally inoculated Canadian chrysotile asbestos dust and orally or subcutaneously administered NDEA has been studied in long-term experiments in Syrian golden hamsters. In animals treated with asbestos only, no lung tumours developed, and single tracheal or laryngeal papillomas were found in only a very few cases. In animals treated with asbestos and NDEA, a synergistic effect which increased the incidence of lung tumours was observed.
摘要
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