Multiple arterial occlusions in a hemophilic patient.

Development of cerebral and coronary arterial occlusion in a hemophilic patient with widespread obliterative arteriosclerosis is described. This observation indicates that even a profound life-long coagulation defect does not afford protection against cerebrovascular and coronary occlusion and raises further questions regarding the rationale of anticoagulant therapy in the management of arteriosclerotic obliterative disease.