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Deoxycytidylate deaminase. Purification and some properties of the enzyme isolated from human spleen.

作者信息

Ellims P H, Kao A Y, Chabner B A

出版信息

J Biol Chem. 1981 Jun 25;256(12):6335-40.

PMID:7240207
Abstract
摘要

相似文献

1
Deoxycytidylate deaminase. Purification and some properties of the enzyme isolated from human spleen.
J Biol Chem. 1981 Jun 25;256(12):6335-40.
2
Reversal of the effect of the allosteric ligands of dCMP-aminohydrolase and stabilization of the enzyme in the T form.
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Kinetic interaction of 5-AZA-2'-deoxycytidine-5'-monophosphate and its 5'-triphosphate with deoxycytidylate deaminase.5-氮杂-2'-脱氧胞苷-5'-单磷酸及其5'-三磷酸与脱氧胞苷酸脱氨酶的动力学相互作用。
Mol Pharmacol. 1984 May;25(3):436-40.
4
Human deoxycytidylate deaminase. Substrate and regulator specificities and their chemotherapeutic implications.人脱氧胞苷酸脱氨酶。底物和调节特异性及其化疗意义。
Mol Pharmacol. 1983 Jan;23(1):159-64.
5
Analysis of competition for substrate sites in an allosteric enzyme with co-operative kinetics. Effects of dAMP and dUMP on donkey spleen deoxycytidylate aminohydrolase.具有协同动力学的变构酶中底物位点竞争分析。dAMP和dUMP对驴脾脱氧胞苷酸氨基水解酶的影响。
Eur J Biochem. 1983 Dec 15;137(3):421-7. doi: 10.1111/j.1432-1033.1983.tb07845.x.
6
Properties of an affinity-column-purified human deoxycytidylate deaminase.
Biochim Biophys Acta. 1993 Mar 5;1162(1-2):161-70. doi: 10.1016/0167-4838(93)90143-f.
7
Hill coefficient ratios give binding ratios of allosteric enzyme effectors; inhibition, activation, and squatting in deoxycytidylate aminohydrolase (EC 3.5.4.12).希尔系数比给出了变构酶效应物的结合比;脱氧胞苷酸氨基水解酶(EC 3.5.4.12)中的抑制、激活和驻留。
Arch Biochem Biophys. 1991 Aug 15;289(1):12-8. doi: 10.1016/0003-9861(91)90435-l.
8
5-AZA-2'-deoxycytidine synergistic action with thymidine on leukemic cells and interaction of 5-AZA-dCMP with dCMP deaminase.5-氮杂-2'-脱氧胞苷与胸苷对白血病细胞的协同作用以及5-氮杂-dCMP与dCMP脱氨酶的相互作用。
Adv Exp Med Biol. 1986;195 Pt B:157-63. doi: 10.1007/978-1-4684-1248-2_24.
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Isolation of a Saccharomyces cerevisiae mutant strain deficient in deoxycytidylate deaminase activity and partial characterization of the enzyme.酿酒酵母中缺乏脱氧胞苷酸脱氨酶活性的突变菌株的分离及该酶的部分特性研究
J Bacteriol. 1984 May;158(2):644-9. doi: 10.1128/jb.158.2.644-649.1984.
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Allosteric transitions associated with the binding of substrate and effector ligands to T2 phage induced deoxycytidylate deaminase.与底物和效应物配体结合到T2噬菌体诱导的脱氧胞苷酸脱氨酶相关的别构转变。
Biochemistry. 1982 Aug 3;21(16):3780-5. doi: 10.1021/bi00259a009.

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Deoxycytidine deaminase-deficient Escherichia coli strains display acute sensitivity to cytidine, adenosine, and guanosine and increased sensitivity to a range of antibiotics, including vancomycin.
缺乏脱氧胞苷脱氨酶的大肠杆菌菌株对胞苷、腺苷和鸟苷表现出急性敏感性,并对包括万古霉素在内的一系列抗生素的敏感性增加。
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Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene.一种人载脂蛋白B mRNA编辑蛋白的二聚体结构及其基因的克隆与染色体定位
Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8522-6. doi: 10.1073/pnas.91.18.8522.
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Human thymidine kinase: purification and some properties of the TK1 isoenzyme from placenta.人胸苷激酶:胎盘来源的TK1同工酶的纯化及某些特性
Mol Cell Biochem. 1982 Jun 11;45(2):113-6. doi: 10.1007/BF00223505.
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Phospholipase C (heat-labile hemolysin) of Pseudomonas aeruginosa: purification and preliminary characterization.铜绿假单胞菌的磷脂酶C(热不稳定溶血素):纯化及初步特性分析
J Bacteriol. 1982 Oct;152(1):239-45. doi: 10.1128/jb.152.1.239-245.1982.
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Kinetic behaviour and allosteric regulation of human deoxycytidylate deaminase derived from leukemic cells.源自白血病细胞的人脱氧胞苷酸脱氨酶的动力学行为和别构调节
Mol Cell Biochem. 1983;57(2):185-90. doi: 10.1007/BF00849195.
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Isolation of a Saccharomyces cerevisiae mutant strain deficient in deoxycytidylate deaminase activity and partial characterization of the enzyme.酿酒酵母中缺乏脱氧胞苷酸脱氨酶活性的突变菌株的分离及该酶的部分特性研究
J Bacteriol. 1984 May;158(2):644-9. doi: 10.1128/jb.158.2.644-649.1984.
9
Thymidine as an anticancer agent, alone or in combination. A biochemical appraisal.胸苷作为一种抗癌剂,单独使用或联合使用。一项生化评估。
Cancer Chemother Pharmacol. 1982 Dec;10(1):1-6. doi: 10.1007/BF00257227.
10
Deoxycytidylate deaminase activity in non-stimulated and phytohemagglutinin-stimulated human lymphocytes, and in leukemic cells.非刺激和植物血凝素刺激的人淋巴细胞以及白血病细胞中的脱氧胞苷酸脱氨酶活性。
Mol Cell Biochem. 1987 Jul;76(1):27-34. doi: 10.1007/BF00219395.