乙炔基自杀底物对睾丸酮假单胞菌δ5-3-酮类固醇异构酶的不可逆失活作用。类固醇-酶加合物的形成机制及性质 - Suppr | 超能文献

Irreversible inactivation of delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni by acetylenic suicide substrates. Mechanism of formation and properties of the steroid-enzyme adduct.

作者信息

Penning T M, Covey D F, Talalay P

出版信息

J Biol Chem. 1981 Jul 10;256(13):6842-50.

Abstract

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Irreversible inactivation of delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni by acetylenic suicide substrates. Mechanism of formation and properties of the steroid-enzyme adduct.乙炔基自杀底物对睾丸酮假单胞菌δ5-3-酮类固醇异构酶的不可逆失活作用。类固醇-酶加合物的形成机制及性质

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Linkage of an acetylenic secosteroid suicide substrate to the active site of delta 5-3-ketosteroid isomerase. Isolation and characterization of a tetrapeptide.乙炔基甾体自杀底物与δ5-3-酮甾体异构酶活性位点的连接。一种四肽的分离与表征。

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Irreversible inhibitors of delta5-3-ketosteroid isomerase: acetylenic and allenic 3-oxo-5,10-secosteroids.δ5-3-酮甾体异构酶的不可逆抑制剂：炔属和联烯属3-氧代-5,10-断甾体

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Letter: Conjugated allenic 3-oxo-5,10-secosteroids. Irreversible inhibitors of delta 5-3-ketosteroid isomerase.

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Inactivation of delta 5-3-ketosteroid isomerase(s) from beef adrenal cortex by acetylenic ketosteroids.

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Letter: Irreversible inhibition of delta-5-3-ketosteroid isomerase by 5,10-secosteroids.信函：5,10-断甾体对δ-5-3-酮甾体异构酶的不可逆抑制作用

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Irreversible active-site-directed inhibition of delta 5-3-ketosteroid isomerase by steroidal 17-beta-oxiranes. Evidence for two modes of binding in steroid-enzyme complexes.

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An active-site-directed irreversible inhibitor of delta 5-3-ketosteroid isomerase.

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