利用淀粉凝胶电泳诊断血管内溶血
Diagnosis of intravascular haemolysis using starch gel electrophoresis.
作者信息
Ali M A, Vanderlinder B
出版信息
Scand J Haematol. 1977 Oct;19(4):343-6. doi: 10.1111/j.1600-0609.1977.tb01484.x.
Abstract
Starch gel electrophoresis was used to screen for intravascular haemolysis in 15 patients with clinical disorders known to be characterized by intravascular haemolysis. Decreased serum haptoglobins, increased free plasma haemoglobin and the presence of methaemalbumin was documented in all 15 patients. It is suggested that starch gel electrophoresis and staining with haem specific stain is a simple and reliable method for confirming intravascular haemolysis.
摘要
采用淀粉凝胶电泳法对15例已知以血管内溶血为特征的临床疾病患者进行血管内溶血筛查。所有15例患者均出现血清触珠蛋白降低、游离血浆血红蛋白升高及高铁血红素白蛋白的存在。提示淀粉凝胶电泳及血红蛋白特异性染色是确认血管内溶血的一种简单可靠的方法。
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