Mesaki N, Kubo T, Iwasaki H
Nihon Sanka Fujinka Gakkai Zasshi. 1980 Jul;32(7):879-85.
We studied about the effects of glucose and amino acid on the fetal weight gain for intrauterine growth retardation (IUGR). Twenty women were diagnosed as IUGR at 30 weeks of gestation. Nine patients were hospitalized and were given 500 ml 10% glucose and 200 ml 12% amino acid intravenously everyday until her delivery (treated group, T group). Other 11 were given no treatment (non-treated group, NT group). The biparietal diameter of the newborn infant in each group was not significantly different. But the birth weight was significantly different (P less than 0.001) between T group (2996 +/- 92 g, Mean +/- SE) and NT group (2490 +/- 65 g). At the gestational weeks in each delivery, the ratio of the discrepancy between the birth weight and the average to the standard deviation (SD) at that weeks were -0.42 +/- 0.20 SD and -1.51 +/- 0.13 SD respectively (P less than 0.001). For the evaluation of the effect of the treatment, the ratio to the estimated fetal weight at the time of IUGR diagnosed was compared with the ratio to the birth weight. T group indicated -1.21 +/- 0.72 SD to -0.42 +/- 0.61 SD (P less than 0.01). NT group indicated -0.55 +/- 0.45 SD to -1.44 +/- 0.24 SD (not significantly). These data suggest that the treatment were apparently effective in increasing the fetal weight.
我们研究了葡萄糖和氨基酸对宫内生长迟缓（IUGR）胎儿体重增加的影响。20名女性在妊娠30周时被诊断为IUGR。9名患者住院，每天静脉输注500毫升10%葡萄糖和200毫升12%氨基酸直至分娩（治疗组，T组）。另外11名未接受治疗（未治疗组，NT组）。每组新生儿的双顶径无显著差异。但T组（2996±92克，均值±标准误）和NT组（2490±65克）的出生体重有显著差异（P＜0.001）。在每次分娩时的孕周，出生体重与该孕周平均体重之差与标准差（SD）的比值分别为-0.42±0.20 SD和-1.51±0.13 SD（P＜0.001）。为评估治疗效果，将IUGR诊断时与出生体重的比值与估计胎儿体重的比值进行比较。T组为-1.21±0.72 SD至-0.42±0.61 SD（P＜0.01）。NT组为-0.55±0.45 SD至-1.44±0.24 SD（无显著差异）。这些数据表明该治疗在增加胎儿体重方面明显有效。
