• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

5-溴脱氧尿苷和氟尿嘧啶对果蝇两个同源异型突变体的抑制作用。

Inhibition of two homeotic mutants of Drosophila by 5-bromodeoxyuridine and fluorouracil.

作者信息

Ibars G C, Selick H E, Kauffman S A

出版信息

J Exp Zool. 1981 May;216(2):261-5. doi: 10.1002/jez.1402160206.

DOI:10.1002/jez.1402160206
PMID:7241065
Abstract

Nasobemia (Ns) and spineless-aristapedia (ssa40a) are dominant and recessive homeotic mutants of Drosophila which convert parts of the antenna to leg structures. Exposure of Ns and ssa40a larvae to half-lethal concentrations of 5-bromodeoxyuridine (BUdR) and flourouracil (FU) together or separately during the presumptive time of gene action suppresses the expressivity and penetrance of the mutants.

摘要

鼻化症（Ns）和无刺触角突变体（ssa40a）是果蝇的显性和隐性同源异型突变体，它们会将触角的部分结构转变为腿部结构。在基因作用的假定时间内，将Ns和ssa40a幼虫分别或同时暴露于半致死浓度的5-溴脱氧尿苷（BUdR）和氟尿嘧啶（FU）下，会抑制突变体的表达率和外显率。

相似文献

1
Inhibition of two homeotic mutants of Drosophila by 5-bromodeoxyuridine and fluorouracil.5-溴脱氧尿苷和氟尿嘧啶对果蝇两个同源异型突变体的抑制作用。
J Exp Zool. 1981 May;216(2):261-5. doi: 10.1002/jez.1402160206.
2
Ultrastructural effects of 5-bromodeoxyuridine and 5-fluorouracil in Drosophila.
Cancer Res. 1973 Feb;33(2):234-48.
3
A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication III. Influence of temperature on the penetrance and expressivity of the Apx and Ns genes.
Sov Genet. 1974 Sep 15;8(10):1252-7.
4
[Formation of a complete mid leg with sternopleura in the antennae region by the mutant Nasobemia (Ns) of Drosophila melanogaster].[黑腹果蝇突变体鼻贫血（Ns）在触角区域形成带有胸膜的完整中腿]
Arch Julius Klaus Stift Vererbungsforsch Sozialanthropol Rassenhyg. 1967;41(2-4):44-54.
5
[Active period of genes during Drosophila ontogenesis. I. Temperature-sensitive period for the spineless effect in aristapedia mutants].
Ontogenez. 1975;6(5):485-91.
6
A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication II. Interaction of the homeotic antennopedix and nasobemia genes with the polycomb, multiple sex comb, aristapedia, and thread genes.
Sov Genet. 1974 Sep 1;8(9):1126-31.
7
Expression of homeotic mutations in duplicated and regenerated antennae of Drosophila melanogaster.黑腹果蝇重复和再生触角中同源异型突变的表达。
J Embryol Exp Morphol. 1975 Apr;33(2):459-69.
8
Morphogenic effects of halogenated thymidine analogues on Drosophila. VI. Causal analysis of bromodeoxyuridine induced growth lesions.
Differentiation. 1975 Aug 11;3(1-3):133-42. doi: 10.1111/j.1432-0436.1975.tb00853.x.
9
[Age specificity of the effect of 5-bromdeoxyuridine on the differentiation and spectra of chromosomal puffs in the salivary glands of Drosophila virilis Sturt. II. Alteration of the puff spectrum in salivary gland chromosomes].[5-溴脱氧尿苷对粗壮果蝇唾液腺染色体疏松区分化及光谱影响的年龄特异性。II. 唾液腺染色体疏松区光谱的改变]
Genetika. 1977;13(9):1596-604.
10
[Time of gene activity during drosophila ontogenesis. III. Temperature-sensitive period of the homeotic mutation nasobemia].[果蝇个体发育过程中基因活动的时间。III. 同源异型突变鼻血症的温度敏感期]
Ontogenez. 1977;8(2):183-6.