Melella A, Basilico L, Lupini A, Renda F
Minerva Med. 1978 Oct 31;69(52):3571-80.
Primary and secondary hyperparathyroidism are both marked by widespread skeletal demineralisation, subperiosteal erosion of the cortex, brown tumours, osteosclerosis, and extraosseous calcification. Differential diagnosis is guided by the different association of these findings. Brown tumours and more extensive erosion are marks of the primary form, whereas osteosclerosis and extra-osseous calcification are a prominent feature of secondary hyperparathyroidism. Radiologists, therefore, should direct their attention to features suggesting the presence of secondary forms in addition to looking for bone alterations associated with hyperparathyroidism.
原发性和继发性甲状旁腺功能亢进均表现为广泛的骨质脱矿、皮质骨骨膜下侵蚀、棕色瘤、骨质硬化和骨外钙化。这些表现的不同组合有助于进行鉴别诊断。棕色瘤和更广泛的侵蚀是原发性甲状旁腺功能亢进的特征,而骨质硬化和骨外钙化是继发性甲状旁腺功能亢进的突出特点。因此,放射科医生在寻找与甲状旁腺功能亢进相关的骨骼改变时,还应关注提示继发性甲状旁腺功能亢进存在的特征。