Igarashi M, O-Uchi T, Smith R J, Stout B E
J Otolaryngol. 1981 Apr;10(2):99-108.
This is a report of the inner ear pathology found in a pair of temporal bones from a deaf mutism case. This patient's spouse and four of six children were deaf mutes. Some members in the succeeding generation were also known to be deaf mutes. The temporal bones (horizontally sectioned) showed the cochleo-saccular degeneration with exactly similar extent bilaterally. The scala media and the saccular space were atrophied, and displaced membranes were attached onto the degenerated sensory epithelia in many areas, but some portion of the scala media exhibited an ectatic view. The cochlear and saccular nerves were severely reduced. In addition to the pathology found in the pars inferior, the internal auditory canal and the cochlear aqueduct were enlarged. All end organs and nerves in the pars superior were intact.
这是一份关于一名聋哑病例颞骨内耳病理学的报告。该患者的配偶及六个孩子中的四个是聋哑人。据了解，其后代中的一些成员也是聋哑人。颞骨（水平切片）显示双侧蜗球囊变性程度完全相似。中阶和球囊腔萎缩，在许多区域，移位的膜附着于变性的感觉上皮，但中阶的某些部分呈现扩张状态。蜗神经和球囊神经严重减少。除了在下半部分发现的病理学改变外，内耳道和蜗水管扩大。上半部分所有的终器和神经均完好无损。
