Hodgkin disease as the terminal malignancy in Richter syndrome.

A case of Richter syndrome in which autopsy revealed typical infiltrates of Hodgkin disease, including Reed-Sternberg cells, is reported. Previous reports of this association have met with skepticism. Clinical findings in patients with Hodgkin infiltrates do not differ from those with histiocytic lymphoma, except for the more frequent occurrence of a declining lymphocyte count. The present case is further evidence that Hodgkin disease does occur as a terminal malignancy in Richter syndrome.