De Kruif A, Kalis C H
Tijdschr Diergeneeskd. 1977 Nov 15;102(22):1299-305.
Various drugs were used in the treatment of 140 cows with cystic ovarian follicles (2.9 per cent of the population) on twenty-five dairy farms during a four-year period. This was done as part of a herd fertility programme. Aanoestrus (approximately sixty days after parturition) was found to be due to cystic follicles in fifty-three cows (7 per cent of the cows examined for anoestrus). An irregular cycle or nymphomania was found to be present in eighty-seven cows (62 per cent). Treatment consisted in intravenous injection of 3,000 I.U. of human chorionic gonadotrophin plus 125 mg. of progesterone (Nymfalon" or intramuscular injection of 0.2 mg. of gonadotrophin-releasing hormone (Lutal". There were no significant differences between the results of the two forms of treatment (Tables 1 and 2), neither as regards becoming pregnant nor where the interval between injection and the next oestrus was concerned. Nine cows which failed to respond to several courses of treatment with Nymfalon or Lutal, were treated with chlormadinone acetate (oral administration of 20 mg. daily for sixteen days). Only two animals became pregnant. Abortion occurred in one of the animals within three months (Table 3).