Farber M, Madanes A, O'Briain D S, Millan V G, Turksoy R N, Rule A H
Obstet Gynecol. 1981 Apr;57(4):521-5.
Testosterone and delta4-androstenedione concentrations, in venous blood obtained by percutaneous retrograde femoral catheterization of the ovarian and adrenal veins bilaterally, demonstrated the left ovary to be the predominant secretory source of androgens in an 18-year-old virilized female. Histologic examination of the excised ovarian tissue revealed asymmetric hyperthecosis ovarii and confirmed the biochemical data. This study demonstrates the accuracy of the venous catheterization method in locating preoperatively the hypersecretory source of androgens in virilized women. The favorable postoperative clinical result emphasizes the importance of an accurate preoperative diagnosis in virilized women even in the absence of ovarian neoplasia.
通过经皮逆行股静脉插管对双侧卵巢静脉和肾上腺静脉采血检测睾酮和δ4-雄烯二酮浓度，结果显示，在一名18岁男性化女性中，左卵巢是雄激素的主要分泌来源。对切除的卵巢组织进行组织学检查发现卵巢卵泡膜细胞增生不对称，这证实了生化检测数据。本研究证明了静脉插管法在术前定位男性化女性雄激素分泌过多来源方面的准确性。术后良好的临床结果强调了即使在没有卵巢肿瘤的情况下，对男性化女性进行准确术前诊断的重要性。
