Ey J L, Smith S M, Fulginiti V A
Pediatrics. 1981 Feb;67(2):285-7.
Varicella hepatitis has been reported frequently in immunocompromised patients and occasionally in adults with varicella pneumonia and/or systemic involvement. However, hepatitis is not generally known to occur in otherwise uncomplicated varicella. Six children are described who had typical varicella in association with transient elevation of liver enzymes. No CNS abnormalities were noted, and all recovered uneventfully. Such patients have previously been described as representing stage I of Reye's syndrome. The authors postulate that hepatitis complicating varicella may well represent a distinct entity which bears no relationship to Reye's syndrome.
水痘性肝炎在免疫功能低下的患者中屡有报道,在患水痘肺炎和/或有全身症状的成人中也偶有发生。然而,一般认为在无其他并发症的水痘患者中不会出现肝炎。本文描述了6名患典型水痘且伴有肝酶短暂升高的儿童。未发现中枢神经系统异常,所有患儿均顺利康复。此前曾将这类患者描述为代表瑞氏综合征的I期。作者推测,水痘并发的肝炎很可能是一种与瑞氏综合征无关的独特病症。