Mach Z, Swierczak J, Pawlik T, Wajdowicz A, Barycz M
Pol J Pharmacol Pharm. 1980 Nov-Dec;32(6):889-91.
The studies of chronic toxicity of the preparation M-71 (Craviten) were carried out on rats and mice. The body weight, absolute and relative weight or organs, haematocrit, the number of erythrocytes and leukocytes, the proportional content of leukocytes, OB value, activity of aminotransferases (AspAT and AlAT), the level of glucose in the blood serum and the histopathology of some organs were investigated. Moreover, in rats receiving M-71 intraperitoneally, the amount of electrolytes and the daily excretion of urine was studied. The results suggest that M-71 did not change the investigated parameters.
对制剂M-71（克拉维坦）进行了大鼠和小鼠慢性毒性研究。研究了体重、器官的绝对重量和相对重量、血细胞比容、红细胞和白细胞数量、白细胞比例含量、OB值、转氨酶（天冬氨酸转氨酶和丙氨酸转氨酶）活性、血清葡萄糖水平以及一些器官的组织病理学。此外，对腹腔注射M-71的大鼠，研究了电解质含量和每日尿量。结果表明，M-71未改变所研究的参数。
