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急性汞蒸气中毒(作者译)

[Acute mercury vapour poisoning (author's transl)].

作者信息

Garnier R, Fuster J M, Conso F, Dautzenberg B, Sors C, Fournier E

出版信息

Toxicol Eur Res. 1981 Mar;3(2):77-86.

PMID:7245189
Abstract

Two persons, exposed to high concentration of mercury vapour in their home developed a few hours later febrile illness with interstitial pneumonitis and mercurial stomatitis. Symptomatic treatment was associated with dimercaprol (BAL) and steroïds; an alveolar washing was performed to remove non-absorbed mercury in the respiratory three which seems to be responsible for the observed inflammatory reaction and, sometimes, the delayed development of fibrosis. A review of the literature revealed that such intoxications had been previously described in about 20 cases. Prognosis depends on the severity of the pulmonary lesions. Fatalities have been described in 9 cases (10%); in 8 cases the victims were young children or old people. An acute gingivo-stomatitis is generally observed. The onset of mercurial encephalopathy is an uncommon feature. Renal disturbances are exceptionally described and always mild. There is no correlation between the clinical condition of the patient and the levels of mercury in the urine.

摘要

两人在家中接触高浓度汞蒸气,数小时后出现发热性疾病,伴有间质性肺炎和汞毒性口炎。对症治疗联合使用了二巯丙醇(BAL)和类固醇;进行了肺泡灌洗以清除呼吸道中未吸收的汞,这些汞似乎是观察到的炎症反应以及有时纤维化延迟发展的原因。文献综述显示,此前已描述过约20例此类中毒病例。预后取决于肺部病变的严重程度。已有9例死亡病例(10%)的报道;其中8例受害者为儿童或老年人。通常会观察到急性龈口炎。汞中毒性脑病的发作是一种不常见的特征。肾紊乱情况罕见且总是轻微的。患者的临床状况与尿汞水平之间没有相关性。

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