Dühmke E, Caliebe W
Strahlentherapie. 1981 May;157(5):297-300.
Fifty cases with malignant tumors of the hypopharynx having been irradiated with cobalt-60 at the Radiological Clinic of the Kiel University between 1965 and 1979 are reported. The cumulative 10-year survival rate amounted to 16%. Age and sex, the histology and mode of growth as well as the stage (mostly III or IV) and the primary site of the tumor had no prognostic significance, whereas the tumor response to treatment proved decisive to the prognosis: of the cases clinically revealing complete regression of the tumor, 32% could finally be regarded as cured. Using sole radiation therapy it was possible to obtain total regression of the tumor in 72% with doses between 1500 and 1650 ret, and in 84% with doses between 1651 and 1800 ret. All the patients with clinically incomplete tumor regression deceased within a year.
本文报告了1965年至1979年间在基尔大学放射科接受钴-60照射的50例下咽恶性肿瘤患者。10年累积生存率为16%。年龄、性别、组织学类型、生长方式、肿瘤分期（大多为III期或IV期）及原发部位对预后均无显著意义，而肿瘤对治疗的反应对预后起决定性作用：临床上肿瘤完全消退的病例中，最终32%可视为治愈。单纯放疗时，剂量在1500至1650拉德之间，72%的患者肿瘤可完全消退；剂量在1651至1800拉德之间，84%的患者肿瘤可完全消退。所有临床上肿瘤消退不完全的患者均在一年内死亡。
