Felix R, Simon H, Hedde J P, Winkler C
Nuklearmedizin. 1978 Sep;17(4):172-7.
Myocardial perfusion studies with labelled particles make a detailed analysis of the distribution of myocardial perfusion possible. Methodical and physiological fundamentals are described and the reliability of the method is shown by double radionuclide imaging. LAD-stenoses (greater than 70%) show a decreased activity in the distal areas of the LAD (on the average 36,5 +/- 10,3% in contrast to 59 +/- in normals). Mean local activity is 14,9 +/- 1,8% within scars. Scars and hemodynamically effective stenoses can be imaged with high sensitivity. Total defects (smaller than 15% of the activity maximum) correspond to a scar. A moderate reduction of uptake (15--50% of the activity maximum) does not allow any differentiation between scar and reversible diminution of perfusion.
用标记颗粒进行心肌灌注研究能够对心肌灌注分布进行详细分析。文中描述了该方法的方法学和生理学基础，并通过双放射性核素成像展示了该方法的可靠性。左前降支狭窄（大于70%）在左前降支远端区域显示活性降低（平均为36.5±10.3%，而正常人为59±）。瘢痕内平均局部活性为14.9±1.8%。瘢痕和血流动力学上有意义的狭窄能够以高灵敏度成像。完全缺损（小于最大活性的15%）对应于瘢痕。摄取的中度降低（最大活性的15 - 50%）无法区分瘢痕和灌注的可逆性降低。
