Matveev Iu A
Vopr Pitan. 1981 Mar-Apr(2):56-60.
Absorption and assimilation of some of fatty acids and fatty acid composition of platelet lipids and red cell stroma were studied in 75 patients suffering from the malabsorption syndrome. The patients were distributed in 4 groups in terms of the disease severity. The patients subjected to an extensive resection of the small intestine and those with stage III enterocolitis manifested malabsorption, because of significant steatorrhea, of food polyunsaturated fatty acids, particularly of linoleic acid. This led to the deranged formation of lipid structures of biomembranes, which is evidenced by the magnitudes of the essential metabolism ratio (EMR). The disease severity was in good agreement with the intensity of steatorrhea and the decrease of EMR. The data obtained form the basis for recommendations on an adequate fatty acid composition of the diet designed for patients with the malabsorption syndrome. It is thus recommended that the diet should include fat products rich in fatty acids with a short- and medium-size carbon chain, oils rich in oleic acid, and be supplemented as well with polyunsaturated fatty acids in the concentrated form ("essentiale" preparations).
对75例吸收不良综合征患者的部分脂肪酸吸收与同化以及血小板脂质和红细胞基质的脂肪酸组成进行了研究。根据疾病严重程度，将患者分为4组。接受小肠广泛切除术的患者和患有Ⅲ期小肠结肠炎的患者由于明显的脂肪泻，出现食物多不饱和脂肪酸，尤其是亚油酸的吸收不良。这导致生物膜脂质结构形成紊乱，这可通过必需代谢率（EMR）的数值得到证明。疾病严重程度与脂肪泻强度和EMR降低情况高度一致。所获得的数据为针对吸收不良综合征患者设计的饮食中适当脂肪酸组成的建议提供了依据。因此，建议饮食应包括富含短链和中链脂肪酸的脂肪产品、富含油酸的油类，同时还应补充浓缩形式的多不饱和脂肪酸（“必需脂肪酸”制剂）。
