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多发性硬化症中的淋巴细胞亚群:使用不同绵羊红细胞进行玫瑰花结试验的变化

Lymphocyte subpopulations in multiple sclerosis: variations in rosette tests using erythrocytes from different sheep.

作者信息

Naess A, Nyland H

出版信息

Acta Pathol Microbiol Scand C. 1980 Dec;88(6):293-7. doi: 10.1111/j.1699-0463.1980.tb00109.x.

DOI:10.1111/j.1699-0463.1980.tb00109.x
PMID:7246144
Abstract

Lymphocytes from 34 patients with active and with stable multiple sclerosis (MS) were examined by rosetting techniques. Patients with active disease had a relative lymphopenia (35 +/- 9%). When tested with erythrocytes (E) from one out of three sheep used, patients with active MS had a decrease in E-rosette forming cells (E-RFC) compared to patients with stable disease and with healthy controls. Other tests (active E-, EAET-, EA-, and EAC-RFC) did not disclose any differences between patients and controls. The results suggest that the origin of the E may be of importance in E-RFC tests.

摘要

采用玫瑰花结技术检测了34例活动期和稳定期多发性硬化症(MS)患者的淋巴细胞。活动期疾病患者存在相对淋巴细胞减少(35±9%)。当用三只绵羊中一只的红细胞(E)进行检测时,与稳定期疾病患者和健康对照相比,活动期MS患者的E玫瑰花结形成细胞(E-RFC)减少。其他检测(活性E-、EAET-、EA-和EAC-RFC)未显示患者与对照之间存在任何差异。结果表明,在E-RFC检测中,E的来源可能很重要。

相似文献

1
Lymphocyte subpopulations in multiple sclerosis: variations in rosette tests using erythrocytes from different sheep.多发性硬化症中的淋巴细胞亚群:使用不同绵羊红细胞进行玫瑰花结试验的变化
Acta Pathol Microbiol Scand C. 1980 Dec;88(6):293-7. doi: 10.1111/j.1699-0463.1980.tb00109.x.
2
The E-rosette test: variations in results using E from different sheep. Effect of FCS and of AET treatment.
Acta Pathol Microbiol Immunol Scand C. 1983 Dec;91(6):367-70.
3
Lymphocyte subpopulations in man: ox erythrocytes as indicators in the EA- and EAC-rosette tests: serological and technical aspects.
Scand J Immunol. 1978;8(3):247-56. doi: 10.1111/j.1365-3083.1978.tb00517.x.
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Effect of AET treatment of sheep erythrocytes on the rosette test in various diseases.
Acta Pathol Microbiol Immunol Scand C. 1982 Dec;90(6):327-30. doi: 10.1111/j.1699-0463.1982.tb01458.x.
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Influence of fetal calf serum on the results of the E rosette test.
Acta Pathol Microbiol Immunol Scand C. 1983 Feb;91(1):77-9.
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Mixed rosette assay for the detection of T mu and T gamma lymphocytes.用于检测Tμ和Tγ淋巴细胞的混合玫瑰花结试验。
J Immunol Methods. 1980;36(3-4):197-209. doi: 10.1016/0022-1759(80)90125-8.
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A methodological study of E-rosette formation using AET-treated sheep red blood cells.一项使用经AET处理的绵羊红细胞进行E花环形成的方法学研究。
J Immunol Methods. 1979 May 10;27(1):61-74. doi: 10.1016/0022-1759(79)90239-4.
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Surface markers on lymphocytes of multiple sclerosis patients.多发性硬化症患者淋巴细胞上的表面标志物。
Clin Exp Immunol. 1975 Aug;21(2):278-83.
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Lymphocyte subpopulations in healthy newborns and in immunohemolytic anemia due to Rh incompatibility.健康新生儿及Rh血型不合所致免疫性溶血性贫血中的淋巴细胞亚群。
Arch Immunol Ther Exp (Warsz). 1981;29(1):21-8.
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Multiple sclerosis. T lymphocytes in cerebrospinal fluid and blood.
Eur Neurol. 1978;17(2):61-6. doi: 10.1159/000114925.

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