Maher J W, Hocking M P, Woodward E R
Ann Surg. 1981 Jul;194(1):64-9. doi: 10.1097/00000658-198107000-00011.
Optimum treatment of patients with esophageal strictures requires of the operating surgeon a wide repertoire of procedures suited to the individual circumstance. The Thal-Nissen procedure should be used in the patient with a longitudinal transmural stricture which cannot be easily dilated. When used in this setting, it widens the distal esophagus with a patch of well vascularized fundus and provides extremely effective protection against gastroesophageal reflux. Sixty-eight patients at the University of Florida underwent combined Thal-Nissen procedures for longitudinal peptic strictures. Operative mortality rate was 4%. The average length of follow-up was 68 months. Fifty-seven of 68 patients had an acceptable result (84%). Four per cent had an early recurrence of their stricture, while an additional 4% had late recurrence of their strictures, after an initially good response period of from two to 11 years. Four of the six patients with poor results had either achalasia, scleroderma, or diffuse esophageal spasm. The combined Thal-Nissen procedure represents the optimum therapy for the patient with an undilatable transmural stricture of the esophagus. When used in this setting, satisfactory results will be achieved in a large majority of patients with an extremely low operative mortality rate. Colonic or jejunal interposition should be reserved for those patients who either fail to respond to a combined Thal-Nissen procedure or who demonstrate sufficiently disordered peristalsis to render the esophagus an unsatisfactory conduit for the passage of food.
食管狭窄患者的最佳治疗需要手术医生具备一系列适合个体情况的手术方法。对于纵向透壁性狭窄且难以扩张的患者,应采用塔尔 - 尼森手术。在此情况下使用该手术时,它会用一片血供良好的胃底来扩大食管远端,并能极其有效地防止胃食管反流。佛罗里达大学的68例患者接受了联合塔尔 - 尼森手术治疗纵向消化性狭窄。手术死亡率为4%。平均随访时间为68个月。68例患者中有57例结果满意(84%)。4%的患者狭窄早期复发,另有4%的患者在最初2至11年的良好缓解期后出现狭窄晚期复发。结果不佳的6例患者中有4例患有贲门失弛缓症、硬皮病或弥漫性食管痉挛。联合塔尔 - 尼森手术是食管不可扩张的透壁性狭窄患者的最佳治疗方法。在此情况下使用时,绝大多数患者将取得满意结果,手术死亡率极低。结肠或空肠间置术应保留给那些对联合塔尔 - 尼森手术无反应或表现出足够紊乱的蠕动致使食管作为食物通道不理想的患者。