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用于食管反流性狭窄的Collis-Nissen联合手术。

The combined Collis-Nissen operation for esophageal reflux strictures.

作者信息

Stirling M C, Orringer M B

机构信息

Section of Thoracic Surgery, University of Michigan Medical Center, Ann Arbor 48109.

出版信息

Ann Thorac Surg. 1988 Feb;45(2):148-57. doi: 10.1016/s0003-4975(10)62427-7.

Abstract

This report evaluates the efficacy of the combined Collis-Nissen operation in achieving long-term reflux control in patients with reflux strictures. A Collis-Nissen procedure with dilation of a reflux stricture was performed in 64 adults. The strictures were mild (easily dilated) in 37, moderate (requiring some force to dilate) in 17, and severe (requiring very forceful dilation) in 10. Two strictures were perforated intraoperatively. There was 1 postoperative death, and 4 patients have been lost to follow-up. The remaining 59 patients have been followed from 2 to 120 months (average, 43 months) after operation. Subjectively, reflux is absent in 48 (81%), mild in 4 (7%), moderate in 5 (9%), and severe in 2 (3%). Objectively, intraesophageal pH studies show good or excellent reflux control in 94% at 1 year and 66% at 2 to 5 years. Dysphagia has been eliminated in 71%, is mild in 10%, moderate (requiring occasional dilation) in 12%, and severe (requiring regular dilations) in 7%. The combined Collis-Nissen operation provides good long-term reflux control and relief of dysphagia in most patients with reflux strictures. However, patients with reflux strictures after previous repairs are likely to have unsatisfactory results and may best be managed with resectional therapy. Resection may also ultimately prove to be a better option for patients with more severe strictures.

摘要

本报告评估了Collis-Nissen联合手术在实现反流性狭窄患者长期反流控制方面的疗效。对64例成人患者进行了伴有反流性狭窄扩张的Collis-Nissen手术。狭窄程度为轻度(易于扩张)的有37例,中度(需要一定力量扩张)的有17例,重度(需要非常用力扩张)的有10例。术中发生2例狭窄穿孔。术后有1例死亡,4例患者失访。其余59例患者在术后2至120个月(平均43个月)进行了随访。主观上,48例(81%)无反流,4例(7%)为轻度反流,5例(9%)为中度反流,2例(3%)为重度反流。客观上,食管内pH值研究显示,1年时94%的患者反流控制良好或极佳,2至5年时为66%。吞咽困难在71%的患者中得到消除,10%的患者为轻度吞咽困难,12%的患者为中度(偶尔需要扩张),7%的患者为重度(需要定期扩张)。Collis-Nissen联合手术在大多数反流性狭窄患者中能提供良好的长期反流控制并缓解吞咽困难。然而,既往接受过修复手术的反流性狭窄患者可能效果不佳,或许最好采用切除治疗。对于狭窄更严重的患者,切除最终可能也是更好的选择。

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