Biggar R J, Nkrumah F K, Neequaye J, Levine P H
Br J Cancer. 1981 May;43(5):632-6. doi: 10.1038/bjc.1981.93.
Between 1965 and 1978, 430 cases of Burkitt's lymphoma were evaluated at the Burkitt Tumour Project, Accra, Ghana. During this period a change in the presenting features occurred, in which abdominal disease increased and facial disease decreased. This change was especially apparent in males, in whom the proportion of cases with abdominal disease more than doubled (chi 2 time trend = 25.99, P = 0.00000017) We speculate that the change may be related to possible changes in BL incidence.
1965年至1978年间,加纳阿克拉的伯基特肿瘤项目评估了430例伯基特淋巴瘤病例。在此期间,首发症状出现了变化,腹部疾病增多而面部疾病减少。这种变化在男性中尤为明显,腹部疾病病例的比例增加了一倍多(卡方时间趋势=25.99,P=0.00000017)。我们推测这种变化可能与伯基特淋巴瘤发病率的可能变化有关。