Skorik V I, Safonova E S, Zelikson B M, Bykova T V, Malikova T M
Biull Eksp Biol Med. 1981 Mar;91(3):277-9.
A Sever-OMP membrane oxygenator (MO) was applied in experiments on 12 dogs to the treatment of a severe hypoventilation hypoxia (over 3 hours). The MO was connected to the arteriovenous shunt established on the femoral vessels. The blood plasma protein spectrum (BPPS) was determined electrophoretically before and after MO connection. BPPS of dogs is characterized by a number of specific features. No signs of blood plasma protein denaturation were found during operation of the Sever-OMP MO that ensures adequate conditions for body existence under hyperventilation. Studies on BPPS facilitate the appraisal of the MO and perfusion conditions.
将一台Sever - OMP膜式氧合器（MO）应用于12只狗的实验中，以治疗严重的通气不足性缺氧（超过3小时）。该膜式氧合器连接到在股血管上建立的动静脉分流处。在连接膜式氧合器前后通过电泳法测定血浆蛋白谱（BPPS）。狗的血浆蛋白谱具有一些特定特征。在Sever - OMP膜式氧合器运行期间未发现血浆蛋白变性的迹象，这确保了在过度通气情况下身体存在的充分条件。对血浆蛋白谱的研究有助于评估膜式氧合器和灌注条件。
