Peyton J W, Crosbie J, Bell T K, Roy A D, Odling-Smee W
Br J Surg. 1981 Jul;68(7):507-9. doi: 10.1002/bjs.1800680721.
Axillary lymphoscintigraphy using 99Tcm antimony sulphide colloid has been carried out in 29 patients with suspected breast cancer and was correlated with histology. Of the 23 with proved tumour, axillary node metastases were found in 19 and, although 10 did have diminished uptake on the side of the lesion, 5 had an equal uptake in both sides and 4 had an increased uptake on the side of the lesion. Further, some of the nodes in which the high uptake had occurred were those heavily infiltrated by tumour. It is concluded that: a, lymphoscintigraphy with antimony sulphide colloid is not a reliable technique for the detection of metastatic disease in the regional nodes; b, any lymphoscintigraphy with this or any other agent requires more meticulous histological correlation than hitherto before it can be assumed to have any proved clinical value.
对29例疑似乳腺癌患者进行了使用99锝硫化锑胶体的腋窝淋巴闪烁显像,并与组织学结果进行了对比。在23例确诊为肿瘤的患者中,19例发现有腋窝淋巴结转移,尽管其中10例病变侧摄取减少,但5例双侧摄取相等,4例病变侧摄取增加。此外,出现高摄取的一些淋巴结是被肿瘤严重浸润的淋巴结。得出以下结论:a,硫化锑胶体淋巴闪烁显像不是检测区域淋巴结转移性疾病的可靠技术;b,使用这种或任何其他试剂的任何淋巴闪烁显像,在被认为具有任何已证实的临床价值之前,都需要比以往更细致地与组织学进行对比。