Davies P, Feisullin S
Brain Res. 1981 Jul 20;216(2):449-54. doi: 10.1016/0006-8993(81)90148-7.
The postmortem stability of alpha-bungarotoxin binding sites was examined in the brains of mice handled under conditions designed to simulate the handling of human autopsy material. No significant changes in the concentration of binding sites were evident up to 24 h after death. No correlation between the number of binding sites and the delay period between death and autopsy was found in studies of frontal cortex or mid-temporal gyrus from normal humans or cases of dementia of the Alzheimer type. Samples of mid-temporal gyrus from demented patients show a significant reduction in the number of binding sites.
在旨在模拟人类尸检材料处理条件下处理的小鼠大脑中，研究了α-银环蛇毒素结合位点的死后稳定性。直至死亡后24小时，结合位点浓度均未出现明显变化。在对正常人或阿尔茨海默病型痴呆病例的额叶皮质或颞中回研究中，未发现结合位点数量与死亡和尸检之间的延迟时间存在相关性。痴呆患者颞中回样本显示结合位点数量显著减少。
