与毛细胞白血病相关的铁粒幼细胞贫血
Sideroblastic anemia associated wtih hairy cell leukemia.
作者信息
Martelli M F, Falini B, Rambotti P, Tonato M, Davis S
出版信息
Cancer. 1981 Aug 1;48(3):762-7. doi: 10.1002/1097-0142(19810801)48:3<762::aid-cncr2820480317>3.0.co;2-5.
Abstract
A patient with leukemic reticuloendotheliosis ("hairy cell" leukemia) with sideroblastic anemia and an epinephrine-induced platelet-aggregation abnormality is presented. Immunologic membrane marker studies supported a B-lymphocyte origin of the hairy cells. It is hypothesized that a defect in the pluripotent marrow stem cell may be responsible for the hairy cell leukemia and for the intrinsic abnormalities in erythrocytes and platelets.
摘要
报告了一名患有白血病性网状内皮细胞增生症（“毛细胞”白血病）、伴有铁粒幼细胞性贫血和肾上腺素诱导的血小板聚集异常的患者。免疫细胞膜标志物研究支持毛细胞起源于B淋巴细胞。据推测，多能骨髓干细胞的缺陷可能是毛细胞白血病以及红细胞和血小板内在异常的原因。
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