Anuras S, Christensen J
Clin Gastroenterol. 1981 Jan;10(1):177-89.
Recurrent or chronic intestinal pseudo-obstruction is not a rare problem. More cases will be recognized and diagnosed when clinicians are more aware of this problem. Medical treatment is unsatisfactory in most cases unless the patients have such treatable associated systemic diseases as myxoedema, hypoparathyroidism or phaeochromocytoma. Intermittent antibiotic therapy may be needed to alleviate diarrhoea or steatorrhoea due to bacterial overgrowth in the small intestine. Surgery may help to relieve the symptoms in those cases with short segmental dilatation of the bowel. Most patients will have an exploratory laparotomy to rule out an organic obstructing lesion. Either a drainage procedure or resection of a short dilated segment should be carried out. Once the diagnosis of chronic intestinal pseudo-obstruction is made, repeated exploratory operations must be avoided. Preoperative antibiotic therapy to treat bacterial overgrowth in the small bowel will reduce postoperative peritonitis from peritoneal soiling by septic small bowel contents.
复发性或慢性肠道假性梗阻并非罕见问题。当临床医生对该问题有更多认识时,将会识别和诊断出更多病例。在大多数情况下,除非患者患有黏液性水肿、甲状旁腺功能减退症或嗜铬细胞瘤等可治疗的相关全身性疾病,否则药物治疗效果并不理想。可能需要间歇性抗生素治疗来缓解因小肠细菌过度生长引起的腹泻或脂肪泻。对于肠道短节段扩张的病例,手术可能有助于缓解症状。大多数患者会接受剖腹探查术以排除器质性梗阻性病变。应进行引流手术或切除短的扩张肠段。一旦确诊为慢性肠道假性梗阻,必须避免重复进行探查性手术。术前使用抗生素治疗小肠细菌过度生长将减少因感染性小肠内容物污染腹膜而导致的术后腹膜炎。