Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Katsushika Medical Center, Japan.
Department of Endoscopy, The Jikei University Katsushika Medical Center, Japan.
Intern Med. 2021 Jul 1;60(13):2039-2046. doi: 10.2169/internalmedicine.6324-20. Epub 2021 Feb 1.
Chronic idiopathic intestinal pseudo-obstruction (CIIP) caused by impaired intestinal peristalsis leads to intestinal obstructive symptoms. A 20-year-old man had marked esophageal dilatation that was found incidentally on chest radiography during a health examination. Chest/abdominal contrast-enhanced computed tomography and endoscopy showed marked esophageal and duodenal dilatation without mechanical obstruction. Upper gastrointestinal series and high-resolution esophageal manometry revealed absent peristalsis in the dilated part. CIIP was suspected in the patient's father, suggesting familial CIIP. The patient likely had signs of pre-onset CIIP. This is the first case of suspected CIIP in which detailed gastrointestinal tract examinations were performed before symptoms appeared.
慢性特发性假性肠梗阻(CIIP)由肠蠕动障碍引起,导致肠梗阻症状。一名 20 岁男性在体检时胸部 X 线检查偶然发现明显的食管扩张。胸部/腹部对比增强 CT 和内镜检查显示明显的食管和十二指肠扩张,无机械性梗阻。上消化道系列和高分辨率食管测压显示扩张部位无蠕动。怀疑患者的父亲患有 CIIP,提示家族性 CIIP。患者可能有前驱期 CIIP 的迹象。这是首例在出现症状之前进行详细胃肠道检查的疑似 CIIP 病例。