Bierman-van Eendenburg M E, Jurgens-van der Zee A D, Olinga A A, Huisjes H H, Touwen B C
Dev Med Child Neurol. 1981 Jun;23(3):296-305.
From a cohort of 1507 infants in the Perinatal Project at University Hospital, Groningen, 80 infants who had been neurologically abnormal in the neonatal period and 80 controls were neurologically re-examined at 18 months of age. Of the 80 abnormal infants, one had died at age three months and 13 other remained abnormal at 18 months, of whom five had severe neurological dysfunction. Two of the control infants had mild abnormalities at 18 months. The rate of false negative results was low, but there was a high rate of false positive results, indicating a high frequency of transient neonatal morbidity. This study demonstrates the sensitivity of the neonatal neurological examination in selecting newborn infants who are in special need of attention.
在格罗宁根大学医院围产期项目的1507名婴儿队列中，80名在新生儿期存在神经异常的婴儿和80名对照婴儿在18个月大时接受了神经学复查。在这80名异常婴儿中，1名在3个月大时死亡，另外13名在18个月时仍存在异常，其中5名有严重神经功能障碍。2名对照婴儿在18个月时存在轻度异常。假阴性结果的发生率较低，但假阳性结果的发生率较高，表明新生儿短暂发病的频率较高。这项研究证明了新生儿神经学检查在挑选特别需要关注的新生儿方面的敏感性。
