Pandolfo N, Bortolotti M, Nebiacolombo C, Labŏ G, Mattioli F
J Chir (Paris). 1981 May;118(5):359-61.
Numerous experimental and clinical observations have established the role of hypertonic duodenal dyskinesia in the etiology of duodenogastric reflux and delayed emptying of the stomach. The original procedure proposed, section of the duodenal muscle fibres, demonstrated a relative hypotonia of the viscera and maintenance of antropyloroduodenal coordination. The present study confirms the effects of extramucosal duodenal myotomy after short- and long-term follow-up in dogs: reduction in gastric emptying time, absence of duodenal stagnation, and lack of morphological changes in the viscera. Unfavorable in duodenogastric reflux, it has favorable effects, on the contrary, on gastric emptying and antral function.
大量实验和临床观察已证实高渗性十二指肠运动障碍在十二指肠-胃反流和胃排空延迟病因学中的作用。最初提出的手术方法,即切断十二指肠肌纤维,显示出内脏相对张力减退以及胃窦-幽门-十二指肠协调性得以维持。本研究通过对犬进行短期和长期随访,证实了黏膜外十二指肠肌切开术的效果:胃排空时间缩短、无十二指肠淤滞以及内脏无形态学改变。它对十二指肠-胃反流不利,相反,对胃排空和胃窦功能有有利影响。