Bencko V, Arbetová D, Skupenová V
J Hyg Epidemiol Microbiol Immunol. 1981;25(2):113-20.
Domesticated rabbits were exposed to natural environmental conditions in an area polluted by emissions from a ferromanganese alloys producing plant. The samples of blood, liver, kidneys, bones, spleen, heart, muscle tissue and hair of rabbits were analyzed, after low-pressure low-temperature, ashing in RF oxygen plasma, for the presence of Mn, Pb, Cr, Cd and Ni, using the Varian Techtron AA 6-D apparatus. Groups of 3 rabbits were killed at the following time intervals: immediately after birth, and then after the exposure of 1, 2, 6 and 12 months. The levels of toxic metals detected in the examined biological samples were compared with those detected in control rabbits from non-polluted area. Contents of the analyzed toxic metals were also determined in animal feed samples as well as in samples of air (24-hour samples), drinking water and soil. The results show that the described biological monitoring might be feasibly coupled with the prepared epidemiological studies conducted in areas contaminated with toxic microelements or other persistent substances that are known to accumulate in the mammalian organism.
将家兔置于受锰铁合金生产厂排放物污染地区的自然环境条件下。对家兔的血液、肝脏、肾脏、骨骼、脾脏、心脏、肌肉组织和毛发样本，在经低压低温、射频氧等离子体灰化处理后，使用瓦里安科技特龙AA 6 - D仪器分析其中锰、铅、铬、镉和镍的含量。每组3只家兔在以下时间间隔处死：出生后立即处死，然后在暴露1个月、2个月、6个月和12个月后处死。将检测的生物样本中有毒金属的含量与来自未受污染地区的对照家兔中检测到的含量进行比较。还测定了动物饲料样本以及空气样本（24小时样本）、饮用水和土壤中分析的有毒金属含量。结果表明，所述生物监测可能与在受有毒微量元素或其他已知在哺乳动物体内蓄积的持久性物质污染地区开展的已准备好的流行病学研究切实可行地结合起来。
