Enhancement of melphalan therapy with glutaminase:asparaginase.
作者信息
Vistica D T, Rabon A, Rabinovitz M
出版信息
Res Commun Chem Pathol Pharmacol. 1978 Oct;22(1):83-92.
PMID:725323
Abstract
Depletion of glutamine with Acinetobacter glutaminase:asparaginase promotes melphalan uptake by and cytotoxicity to murine L1210 cells in vitro. Combined treatment of tumor bearing mice with these two agents increases the therapeutic response.
摘要
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