Miah A H, Spradbrow P B
Res Vet Sci. 1978 Sep;25(2):253-4.
Akabane virus produced either death or developmental abnormalities including arthrogryposis in chicken embryos inoculated by the yolk sac route when four days old. The effects depended on the dose of virus. Yolk sac inoculation of seven-day-old embryos did not result in abnormal embryos, but some chickens were viraemic when they hatched. Inoculation of older embryos intravenously, into the allantoic cavity, or onto the chorioallantoic membrane had no effect on the embryo and akabane virus was not recovered.
当用卵黄囊途径接种4日龄鸡胚时，赤羽病毒会导致鸡胚死亡或出现包括关节弯曲在内的发育异常。这些影响取决于病毒剂量。对7日龄胚胎进行卵黄囊接种不会产生异常胚胎，但有些鸡在孵化时出现病毒血症。对较大的胚胎进行静脉接种、尿囊腔接种或绒毛尿囊膜接种对胚胎没有影响，且未分离到赤羽病毒。
