Jambart S, Draoui F, Hamon P, Heshmati H M, Turpin G, de Gennes J L
Nouv Presse Med. 1981 May 2;10(20):1643-4.
The authors draw attention to the fact that the decrease in 17-hydroxycorticosteroids and 17-ketosteroids observed in patients under meprobamate treatment is probably due to chemical interference with assay methods, since normal response to metyrapone indicates that the adrenal function is unimpaired. The asthenia usually reported by these patients is due to depression and should not be blamed on deficiency of the adrenal cortex.
作者提请注意这样一个事实,即接受眠尔通治疗的患者中观察到的17-羟皮质类固醇和17-酮类固醇的减少可能是由于对检测方法的化学干扰,因为对甲吡酮的正常反应表明肾上腺功能未受损。这些患者通常报告的乏力是由抑郁引起的,不应归咎于肾上腺皮质功能不足。