Tanaka H, Nasu I, Hayakawa H, Miyasaka T
Nucleic Acids Symp Ser. 1980(8):s33-6.
2',3'-O-Isopropylideneuridine, upon lithiation and subsequent alkylation, was transformed to 6-alkyl derivatives in a regiospecific manner. After acidic treatment of the acetonides, 6-alkyluridines (methyl, ethyl, propyl, isopropyl, butyl, secbutyl, and hexan-3-yl) were obtained. 5'-Deoxy-6-alkyluridines (methyl, ethyl, and isopropyl) were also prepared by the same route from 5'-deoxy-2',3'-O-isopropylideneuridine.
