Marconi G, Nuzzaci G, Iacopetti L, Chiriatti G P, Briani S, Masi R, Faleri A
Riv Patol Nerv Ment. 1981 Jul-Aug;101(4):165-70.
The diagnostic value of radioisotopic cerebral angioscintigraphy (R.A.) and of Doppler CW (D.C.W.) techniques to identify stenosis of the internal carotid artery in its extracranial course was studied in 97 patients with ischaemic lesions (50 T.I.A. and 47 Complete Stroke). The results of R.A. and D.C.W. were compared with those of contrast carotid-angiography (C.A.). C.A. revealed stenosis above 50% or complete occlusion in 22% of cases, whereas D.C.W. and R.A. showed flow reduction in 27% and 48% of the cases respectively. In T.I.A., C.A. positivity went down to 8%; D.C.W. to 16%; and R.A. to 34%. In "Complete Stroke" positivity was 36% for C.A.; 41% for D.C.W.; and 62% for R.A. There was a high number of false positive findings with D.C.W. (8) but even more with R.A. (27). False negative findings occurred only in two cases with R.A. These data confirm the diagnostic value of these two noninvasive techniques to identify haemodynamically carotid stenosis. The use of both methods can reduce error due to false negativity. The rather marked frequency of false positivity, particularly with reference to R.A. doesn't affect the diagnostic value of the two methods.
对97例有缺血性病变（50例短暂性脑缺血发作和47例完全性卒中）的患者，研究了放射性同位素脑血管闪烁造影术（R.A.）和连续波多普勒（D.C.W.）技术对识别颈内动脉颅外段狭窄的诊断价值。将R.A.和D.C.W.的结果与颈动脉造影（C.A.）的结果进行了比较。C.A.显示22%的病例狭窄超过50%或完全闭塞，而D.C.W.和R.A.分别显示27%和48%的病例血流减少。在短暂性脑缺血发作中，C.A.阳性率降至8%；D.C.W.降至16%；R.A.降至34%。在“完全性卒中”中，C.A.阳性率为36%；D.C.W.为41%；R.A.为62%。D.C.W.有大量假阳性结果（8例），但R.A.更多（27例）。仅在2例R.A.病例中出现假阴性结果。这些数据证实了这两种非侵入性技术对识别血流动力学性颈动脉狭窄的诊断价值。两种方法联合使用可减少假阴性导致的误差。假阳性的发生率相当高，尤其是R.A.，但这并不影响这两种方法的诊断价值。
