Torrington K G, Hooper R G
South Med J. 1978 Dec;71(12):1487-8. doi: 10.1097/00007611-197812000-00013.
The records of patients who had transbronchial lung biopsy at Walter Reed Army Medical Center between January 1974 and September 1977 were retrospectively reviewed. Nine patients were found whose clinical and radiographic presentations were compatible with lymphangitic carcinomatosis. In five patients in lymphangitic spread of carcinoma was diagnosed from transbronchial lung biopsy specimens. A single patient had a false-negative biopsy, proven at autopsy three weeks later. The other three patients with negative biopsies are alive and receiving chemotherapy 12 months later (two patients) or are lost to follow-up (one patient). Transbronchial lung biopsy is an accurate procedure for diagnosing lymphangitic carcinomatosis. In addition, aggressive chemotherapy should not be used in these patients without a tissue diagnosis.
回顾性分析了1974年1月至1977年9月在沃尔特·里德陆军医疗中心接受经支气管肺活检的患者记录。发现9例患者的临床和影像学表现与淋巴管癌病相符。经支气管肺活检标本诊断出5例患者存在癌性淋巴管播散。1例患者活检结果为假阴性，3周后尸检证实。另外3例活检阴性的患者12个月后仍存活，其中2例正在接受化疗，1例失访。经支气管肺活检是诊断淋巴管癌病的准确方法。此外，在没有组织诊断的情况下，不应在这些患者中使用积极的化疗。
