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棘颚口线虫幼虫期在实验动物中的致病性及向中枢神经系统移行的研究

Study on pathogenicity and central nervous system migration of the larval stage of Gnathostoma spinigerum in experimental animals.

作者信息

Bunnag T, Punyagupta S, Thirachandra S

出版信息

Southeast Asian J Trop Med Public Health. 1981 Mar;12(1):63-8.

PMID:7256356
Abstract

Studies were conducted on the pathogenicity and the route of migration to the central nervous system by the immature larval stage of G.spinigerum in experimental animals. Five mice and one rat showed signs of nervous tissue damage and CNS involvement. The significant findings were massive haemorrhagic areas and blood clot around large lower nerve trunk and spinal cord invasion by the worm. The possible roles of the immature larval stages of G.spinigerum in human was discussed.

摘要

对棘口线虫未成熟幼虫阶段在实验动物中的致病性及向中枢神经系统的迁移途径进行了研究。五只小鼠和一只大鼠出现了神经组织损伤和中枢神经系统受累的迹象。重要发现为大的下神经干周围出现大量出血区和血凝块,以及蠕虫对脊髓的侵袭。文中讨论了棘口线虫未成熟幼虫阶段在人类中的可能作用。

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1
Study on pathogenicity and central nervous system migration of the larval stage of Gnathostoma spinigerum in experimental animals.棘颚口线虫幼虫期在实验动物中的致病性及向中枢神经系统移行的研究
Southeast Asian J Trop Med Public Health. 1981 Mar;12(1):63-8.
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Fine structures of Gnathostoma Spinigerum: a comparative SEM study between an adult worm and a third stage larva.棘颚口线虫的精细结构:成虫与第三期幼虫的扫描电镜比较研究
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