Keagy B A, Pharr W F, Thomas D, Bowes D E
Am J Surg. 1981 Jul;142(1):158-61. doi: 10.1016/s0002-9610(81)80031-1.
The systolic ankle pressure response to thigh cuff occlusion (reactive hyperemia test) was compared with a similar measurement after treadmill exercise in 48 limbs of 24 normal volunteers. The reactive hyperemia test was then performed on 26 legs in 16 patients with clinical evidence of arterial disease of the leg and abnormal treadmill tests (mean decrease 39 +/- 24 percent). No decrease in pressure occurred in normal subjects after exercise. All control subjects demonstrated a decrease in pressure after thigh cuff occlusion (34 +/- 7.9 percent). The percent pressure decrease during reactive hyperemia in the abnormal group was significantly lower (49.7 +/- 19 percent; p less than 0.001). There was a high correlation between the percent decrease in pressure during reactive hyperemia and the decrease after exercise in the claudicants (r = 0.69; p less than 0.001). However, the percent pressure decrease in 13 of the 26 abnormal patients fell within 2 standard deviations of the reactive hyperemia control group mean. The range of the pressure decreases in these 13 patients, 16 to 48 percent, was shared by 47 of the 48 normal subjects. The findings in this study are inconsistent with those in previously published reports and suggest that reactive hyperemia testing cannot be used interchangeably with the treadmill exercise test.
在24名正常志愿者的48条肢体中，比较了大腿袖带阻断后收缩期踝压反应（反应性充血试验）与跑步机运动后类似测量结果。然后，对16例有腿部动脉疾病临床证据且跑步机试验异常（平均下降39±24%）的患者的26条腿进行了反应性充血试验。正常受试者运动后压力未下降。所有对照受试者在大腿袖带阻断后压力均下降（34±7.9%）。异常组反应性充血期间压力下降百分比显著更低（49.7±19%；p<0.001）。跛行患者反应性充血期间压力下降百分比与运动后下降之间存在高度相关性（r = 0.69；p<0.001）。然而，26例异常患者中有13例的压力下降百分比落在反应性充血对照组平均值的2个标准差范围内。这13例患者压力下降范围为16%至48%，48例正常受试者中有47例也在此范围内。本研究结果与先前发表的报告不一致，表明反应性充血试验不能与跑步机运动试验互换使用。
