Ledsome J R, Sharp J M
Am Rev Respir Dis. 1981 Jul;124(1):41-4. doi: 10.1164/arrd.1981.124.1.41.
Measurements of pulmonary function were made on patients within 1 wk, 3 wk, 5 wk, 3 months, and 5 months of spinal cord injury. In patients with functionally complete transection of the cord between segment C5 and C6, the vital capacity was 30% of predicted in the first week after injury. Patients with injuries at C4 had smaller vital capacities. A significant increase in vital capacity occurred within 5 wk of injury with an approximate doubling of vital capacity 3 months after injury. Expiratory flow rates were directly dependent upon vital capacity. There was a high incidence of arterial hypoxemia, in the acute stage, even in patients with adequate ventilatory ability and normocarbia.
在脊髓损伤后1周、3周、5周、3个月和5个月对患者进行肺功能测量。在C5和C6节段之间脊髓功能完全横断的患者中,损伤后第一周的肺活量为预测值的30%。C4损伤的患者肺活量较小。损伤后5周内肺活量显著增加,损伤后3个月肺活量大约翻倍。呼气流量率直接取决于肺活量。在急性期,即使是通气能力正常且血碳酸正常的患者,动脉低氧血症的发生率也很高。