Bonafé J L, Touron P, Viraben R, Voigt J J, Rumeau M, Krempf M
Ann Dermatol Venereol. 1981;108(4):363-8.
This clinical report concerns a 57 year old woman with dermatomyositis and cardiac involvement. After an apparent clinical and biological improve of the muscular and myocardic symptoms, a pulmonary involvement was reported. There was a persistent high rate of lacticodeshydrogenase serum activity. Then, cutaneous ulcerations and necrosis appeared on the extremities of limbs. Dermatomyositis associated with cutaneous necrosis and pulmonary fibrosis has a very severe prognosis.
本临床报告涉及一名57岁患有皮肌炎并伴有心脏受累的女性。在肌肉和心肌症状出现明显的临床及生物学改善后，报告出现了肺部受累情况。血清乳酸脱氢酶活性持续处于较高水平。随后，四肢出现皮肤溃疡和坏死。伴有皮肤坏死和肺纤维化的皮肌炎预后非常严重。
