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急性心肌梗死后的动态与静态运动血流动力学

Dynamic and static exercise haemodynamics after acute myocardial infarction.

作者信息

Korhonen U R

出版信息

Ann Clin Res. 1980 Aug;12(4):152-9.

PMID:7259081
Abstract

The cardiovascular responses to dynamic and static exercises were studied in 20 patients by exercise tests performed at 3 weeks and 12 weeks after acute myocardial infarction. The left ventricular size and volume output were determined by radiocardiography. The mean cardiac output during dynamic exercise at the second study was 24% (p less than 0.05) higher than at the first study, mainly because the peak heart rate was 19% (p less than 0.05) higher. The left ventricular end-diastolic volume or its response to ergometric exercise did not change during the 3-month follow-up and the ejection fraction and stroke volume showed minor changes only. During static exercise a 3% better increase in cardiac output was seen from 3 to 12 weeks, without any improvement in ejection fraction. At the 12-week study the changes in cardiac performance during ergometric exercise were not related to the site of infarction or drug therapy. During static exercise slight improvement of cardiac output, stroke volume and ejection fraction responses were seen in the course of time, but only in the patients with inferior infarction and in those not receiving digoxin and/or diuretics. The mean cardiac output during dynamic exercise improved by one-quarter, mainly due to a higher peak heart rate, in the course of the 3-month follow-up after myocardial infarction. Otherwise, haemodynamic variables during dynamic or static exercises within 3 months showed insignificant sequential changes only.

摘要

通过在急性心肌梗死后3周和12周进行运动测试,对20例患者的心血管对动态和静态运动的反应进行了研究。通过放射性心动图测定左心室大小和心输出量。第二次研究中动态运动期间的平均心输出量比第一次研究高24%(p<0.05),主要是因为峰值心率高19%(p<0.05)。在3个月的随访期间,左心室舒张末期容积或其对测力运动的反应没有变化,射血分数和每搏输出量仅显示轻微变化。在静态运动中,从3周到12周心输出量增加了3%,射血分数没有任何改善。在12周的研究中,测力运动期间心脏功能的变化与梗死部位或药物治疗无关。在静态运动中,随着时间的推移,心输出量、每搏输出量和射血分数反应略有改善,但仅见于下壁梗死患者以及未接受地高辛和/或利尿剂治疗的患者。在心肌梗死后3个月的随访过程中,动态运动期间的平均心输出量提高了四分之一,主要是由于较高的峰值心率。否则,3个月内动态或静态运动期间的血流动力学变量仅显示出不显著的顺序变化。

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