Keough E M, Wood B G
Tissue Cell. 1978;10(3):563-70. doi: 10.1016/s0040-8166(16)30349-4.
This investigation was designed to characterize changes due to adrenalectomy and cortisol treatment in cell types, other than corticotrophs, in the anterior pituitary of the mouse. Cortisol injections resulted in a reduced number of mammotrophs and an increased number of somatotrophs. By 5 days post-adrenalectomy an increase in the number of mammotrophs and a decrease in the number of somatotrophs was observed. No changes were noted in the number of gonadotrophs or thyrotrophs due to either adrenalectomy or cortisol treatment.
本研究旨在描述小鼠垂体前叶中除促肾上腺皮质激素细胞外的其他细胞类型因肾上腺切除和皮质醇治疗而发生的变化。注射皮质醇导致催乳素细胞数量减少，生长激素细胞数量增加。肾上腺切除术后5天，观察到催乳素细胞数量增加，生长激素细胞数量减少。肾上腺切除或皮质醇治疗均未导致促性腺激素细胞或促甲状腺激素细胞数量发生变化。
