Dorofeev A A
Arkh Anat Gistol Embriol. 1981 Mar;80(3):82-8.
Vascular reaction of the liver has been studied in dogs, died and sacrificed during various periods of the burn disease; quantitative characteristics of vascular changes are presented. The data obtained demonstrate that during the whole course of the disease there is a sharp hepatic plethora and sinusoid dilatation demonstrated to a greater extent in the died than in the sacrificed animals. A prolonged capillary congestion (took place in the died animals) is accompanied by more pronounced tissue changes (in comparison with the sacrificed animals) in the form of large foci of albuminous dystrophy and necrotic processes. A suggestion is made that such morphological indices as sharp dilatation of the interlobular arteries and sinuses with pronounced phenomena of plethora, thrombosis of the portal vein branches, large focal hemorrhage could be considered as critical points in adaptation of the peripheral circulation.
对烧伤病程不同阶段死亡和处死后的犬肝脏血管反应进行了研究,并给出了血管变化的定量特征。所获数据表明,在疾病的整个过程中,肝脏均出现明显充血,窦状隙扩张,在死亡动物中比处死后的动物更为明显。在死亡动物中出现的持续性毛细血管充血,伴有更明显的组织变化(与处死后的动物相比),表现为大片白蛋白营养不良和坏死灶。有人提出,诸如小叶间动脉和窦状隙明显扩张并伴有明显充血现象、门静脉分支血栓形成、大片局灶性出血等形态学指标,可被视为外周循环适应的关键点。