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[脑桥源性共轭侧视麻痹:内侧纵束的神经解剖学探讨]

[Paralysis of the conjugated lateral gaze of pontile origin: neuroanatomical discussion of the fasciculus longitudinalis medialis].

作者信息

Faccio E J, Kriguer N, Herskovits E

出版信息

Arq Neuropsiquiatr. 1981 Mar;39(1):89-100. doi: 10.1590/s0004-282x1981000100010.

Abstract

The case of a patient with paralysis of the lateral gaze to the left, paresis of both eyes when he tried to look upwards and a disfunction of the cerebellum to the left, is reported. During the evolution the paresia of both eyes when the patient looked upwards and the disfunction of the cerebellum disappeared, but the paralysis of the lateral gaze to the left, remained. Later on the patient went a little confuse, did not understand what other persons spoke to him, and speak badly. The necropsy showed one old infarct in the medial longitudinal fasciculus in the left, the same type of lesion in the ventral part of the upper pons which was also to the left and demyelinization of the motor lemniscus of the same side. It was also seen a more recent infarct in the transverse gyrus of the left cerebral hemisphere and also the white matter below it. The study of the medial longitudinal fasciculus by means of the secondary degeneration showed that it was crossed above the 6 degrees nuclei, but was straight to the contrary of what is said about it. The authors also observe that the cells of the interstitial nucleus of Cajal were in chromatolysis. These findings justify the syndrome and the absence of the internuclear anterior ophthalmoplegia to the right.

摘要

报告了一例患者,其左眼外展麻痹,向上看时双眼轻瘫,左侧小脑功能障碍。在病情发展过程中,患者向上看时双眼轻瘫及小脑功能障碍消失,但左眼外展麻痹仍存在。后来患者出现轻度意识模糊,听不懂别人对他说的话,且言语不清。尸检显示左侧内侧纵束有一处陈旧性梗死灶,脑桥上段腹侧同一侧也有相同类型的病变,以及同侧运动丘系脱髓鞘。还在左侧大脑半球横回及其下方白质发现一处较新的梗死灶。通过继发性变性对内侧纵束的研究表明,它在展神经核上方交叉,但与通常所说的情况相反,是直行的。作者还观察到 Cajal 间质核的细胞出现染色质溶解。这些发现解释了该综合征以及右侧核间性前眼肌麻痹的缺失。

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