未灌注的枪乌贼轴突中钠电流的不完全失活。
Incomplete inactivation of sodium currents in nonperfused squid axon.
作者信息
Shoukimas J J, French R J
出版信息
Biophys J. 1980 Nov;32(2):857-62. doi: 10.1016/S0006-3495(80)85021-1.
Abstract
Perfused squid axons in which K-conductance is blocked show, under voltage clamp, incomplete inactivation of the sodium conductance. The presence of this phenomenon in nonperfused axons was found by comparing membrane current records before and after tetrodotoxin addition to the bathing solution. Sodium currents in nonperfused axons are comparable in behavior at positive potentials to those seen in Cs-perfused axons.
摘要
在电压钳制下，钾离子电导被阻断的灌注鱿鱼轴突显示出钠电导的不完全失活。通过比较向浴液中添加河豚毒素前后的膜电流记录，发现在非灌注轴突中存在这种现象。非灌注轴突中的钠电流在正电位下的行为与铯灌注轴突中的钠电流相当。
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Negative conductance caused by entry of sodium and cesium ions into the potassium channels of squid axons.钠离子和铯离子进入鱿鱼轴突的钾通道所引起的负电导。
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