外周剥夺对哺乳动物运动神经元发育的影响。
Effect of peripheral deprivation on mammalian motoneurone development.
作者信息
McLennan I S, Hendry I A
出版信息
Brain Res. 1981 Jun;227(3):440-3. doi: 10.1016/0165-3806(81)90083-3.
Foetal rat hindlimbs were removed at 18 days gestation to determine the effect of target tissue removal on the development of mammalian motoneurones. At 25 days postnatal there was a large reduction in the numbers of motoneurones with a corresponding drop in the activity of choline acetyltransferase as well as in the total protein content on the ipsilateral side of the spinal cord. These results show that in mammals, as in other vertebrates, the size of a neuronal population is regulated by the size of the peripheral field innervated.
在妊娠18天时切除胎鼠后肢，以确定去除靶组织对哺乳动物运动神经元发育的影响。出生后25天时，运动神经元数量大幅减少，脊髓同侧的胆碱乙酰转移酶活性以及总蛋白含量相应下降。这些结果表明，在哺乳动物中，与其他脊椎动物一样，神经元群体的大小受其支配的外周区域大小的调节。
Zotero 插件