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[接触蛋白对DNA合成的组织特异性抑制作用,接触蛋白是具有组织特异性黏附活性的因子]

[Tissue-specific inhibition of DNA synthesis by contactins, factors that possess tissue-specific adhesive activity].

作者信息

Malenkov A G, Modianova E A, Iamskova V P

出版信息

Tsitologiia. 1978 Aug;20(8):957-61.

PMID:726070
Abstract

Highly purified factors extracted from the liver and lungs of adult rats, tissue-specifically increasing the stability of intercellular contacts and of cell plasma membranes to mechanical disruption, were found to decrease, in the same manner, the labeling index (LI) in explants of the embryonic tissue of mice. The comparison of the action of these factors on the LI, and on mechanical properties of the tissue has shown that the latter effect is manifested earlier than the former one.

摘要

从成年大鼠的肝脏和肺中提取的高度纯化因子,能组织特异性地增强细胞间接触以及细胞质膜对机械破坏的稳定性,结果发现这些因子以同样的方式降低了小鼠胚胎组织外植体中的标记指数(LI)。对这些因子对标记指数和组织力学特性作用的比较表明,后一种效应比前一种效应出现得更早。

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